At 12:30AM LAFD Rescue Ambulance 7 notified dispatch they were involved in a traffic collision on Van Nuys Blvd & San Fernando Rd, when a solo pickup truck struck the rescue. A total of four patients were involved two of which required immediate attention with extrication needed to free them from the vehicle. Two firefighter personnel had injuries at the time of the crash. 4 patients were taken to the hospital. LAPD is onscene handling the crash investigation.